Overview
Researchers in copper-dependent peptide biology can buy GHK-Cu research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. GHK-Cu (glycyl-L-histidyl-L-lysine copper(II)) is a naturally occurring tripeptide with copper-binding activity, with a molecular weight of 340.4 Da (free peptide) or 403.9 Da as the copper(II) complex.
Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.
Research Background
The GHK tripeptide was originally isolated from human plasma. The copper-bound form (GHK-Cu) is the bioactive species investigated in regenerative and dermal research. The compound features prominently in research blends including the Glow Blend (with BPC-157 and TB-500) and the KLOW Blend (with KPV, BPC-157, and TB-500).
Mechanism of Action (Research Context)
Mechanism research investigates GHK-Cu modulation of copper-dependent metalloproteinase (MMP/TIMP) activity, stimulation of collagen type I/III gene expression in fibroblasts, antioxidant pathway activation, and angiogenesis induction. The copper-binding chemistry is central to the mechanism and distinguishes GHK-Cu from non-metal-binding peptides.
Research Applications
- Copper-dependent metalloproteinase activity research
- Collagen type I/III synthesis pathway stimulation studies
- Skin remodelling MMP/TIMP gene expression modulation research
- Angiogenesis induction pathway investigation
- Multi-compound research via Glow Blend and KLOW Blend
Compound Specifications
| Molecular Weight | 340.4 Da (free peptide) / 403.9 Da (copper complex) |
| Sequence / Composition | Glycyl-L-histidyl-L-lysine (GHK) bound to copper(II) |
| Appearance | Blue-green powder (copper complex form) |
| Purity | ≥ 99% (HPLC verified) |
| Storage | -20 °C, protect from light |
| Format | Lyophilized powder in sterile vial |
Quality Assurance
Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.
Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.
Frequently Asked Questions
Buy GHK-Cu copper tripeptide research USA COA?
Advanced Peptide Science supplies GHK-Cu at 99%+ HPLC-verified purity (as the blue-green copper complex form) with batch-specific COA available on request.
GHK-Cu collagen wound healing research — mechanism?
GHK-Cu binds copper(II) and modulates copper-dependent metalloproteinase activity (MMP/TIMP balance), stimulates collagen type I/III gene expression in fibroblasts, and induces angiogenesis. The copper-binding chemistry is central to its activity.
Is GHK-Cu approved for human use?
Advanced Peptide Science supplies GHK-Cu exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.

