Snap-8

Overview

Researchers in SNARE-complex biology and neurotransmitter-release pharmacology can buy Snap-8 research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. Snap-8 (acetyl glutamyl heptapeptide-3, sequence Ac-EEMQRRA-NH2, MW 1075.2 Da) is a synthetic octapeptide analogue of SNAP-25.

Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.

Research Background

Snap-8 mimics the N-terminal region of SNAP-25 (synaptosomal-associated protein, 25 kDa), a component of the SNARE complex that mediates synaptic vesicle fusion. The peptide is investigated as a competitive disruptor of SNARE-complex assembly — a research approach distinct from neurotoxin-mediated SNARE disruption.

Mechanism of Action (Research Context)

Mechanism research investigates Snap-8 competition with native SNAP-25 for incorporation into the SNARE complex, reducing complex assembly efficiency and downstream vesicle fusion. Acetylcholine-release inhibition at the neuromuscular junction is the most-studied downstream endpoint in preclinical models.

Research Applications

• SNARE complex assembly pharmacology research
• Vesicle fusion pathway preclinical investigation
• Acetylcholine release inhibition mechanism studies at the neuromuscular junction
• Comparative neurotransmitter-release inhibitor research
• SNAP-25 analogue structure-activity relationship studies

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

Buy Snap-8 anti-wrinkle research peptide USA COA?

Advanced Peptide Science supplies Snap-8 at 99%+ HPLC-verified purity with batch-specific COA available on request.

SNAP-25 analogue neurotransmitter inhibitor research — mechanism?

Snap-8 mimics the N-terminal region of SNAP-25 and competitively disrupts SNARE-complex assembly. Reduced SNARE complex assembly inhibits synaptic vesicle fusion and downstream acetylcholine release — a research mechanism distinct from neurotoxin-mediated SNARE disruption.

Is Snap-8 approved for human use?

Advanced Peptide Science supplies Snap-8 exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.