Snap-8

Overview

Researchers in SNARE-complex biology and neurotransmitter-release pharmacology can buy Snap-8 research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. Snap-8 (acetyl glutamyl heptapeptide-3, sequence Ac-EEMQRRA-NH2, MW 1075.2 Da) is a synthetic octapeptide analogue of SNAP-25.

Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.

Research Background

Snap-8 mimics the N-terminal region of SNAP-25 (synaptosomal-associated protein, 25 kDa), a component of the SNARE complex that mediates synaptic vesicle fusion. The peptide is investigated as a competitive disruptor of SNARE-complex assembly — a research approach distinct from neurotoxin-mediated SNARE disruption.

Mechanism of Action (Research Context)

Mechanism research investigates Snap-8 competition with native SNAP-25 for incorporation into the SNARE complex, reducing complex assembly efficiency and downstream vesicle fusion. Acetylcholine-release inhibition at the neuromuscular junction is the most-studied downstream endpoint in preclinical models.

Research Applications

• SNARE complex assembly pharmacology research
• Vesicle fusion pathway preclinical investigation
• Acetylcholine release inhibition mechanism studies at the neuromuscular junction
• Comparative neurotransmitter-release inhibitor research
• SNAP-25 analogue structure-activity relationship studies

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

Buy Snap-8 anti-wrinkle research peptide USA COA?

Advanced Peptide Science supplies Snap-8 at 99%+ HPLC-verified purity with batch-specific COA available on request.

SNAP-25 analogue neurotransmitter inhibitor research — mechanism?

Snap-8 mimics the N-terminal region of SNAP-25 and competitively disrupts SNARE-complex assembly. Reduced SNARE complex assembly inhibits synaptic vesicle fusion and downstream acetylcholine release — a research mechanism distinct from neurotoxin-mediated SNARE disruption.

Is Snap-8 approved for human use?

Advanced Peptide Science supplies Snap-8 exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.

For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent.