AOD-9604

Overview

Researchers investigating lipolytic peptide fragments can buy AOD-9604 research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. AOD-9604 (Anti-Obesity Drug 9604) is a synthetic 16-amino-acid fragment corresponding to the C-terminal region of human growth hormone (positions 176-191), with a molecular weight of 1815.1 Da.

Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.

Research Background

AOD-9604 was developed from research into separating the lipolytic activity of human growth hormone from its IGF-1-mediated growth signalling. The 16-residue C-terminal fragment retains the lipolytic and lipogenesis-inhibition activity of the parent hGH molecule but does not bind the GH receptor in a manner that activates the IGF-1 axis — making it a useful research tool for adipose tissue biology investigation without the confounding effects of full-length hGH.

Mechanism of Action (Research Context)

Mechanism research investigates AOD-9604 stimulation of lipolysis in adipocytes and inhibition of lipogenesis pathways. Unlike intact human growth hormone, the fragment does not activate IGF-1-mediated signalling, providing a research tool for adipose tissue biology investigation isolated from broader GH effects. Beta-adrenergic receptor cross-talk and cAMP signalling in adipocytes are areas of active preclinical investigation.

Research Applications

• Adipocyte lipolysis and lipogenesis-inhibition pathway research
• Adipose tissue biology investigation without IGF-1 axis confounders
• Comparative research vs full-length hGH in lipid metabolism models
• Combined investigation with GLP-1 compounds via Metabolic Blend
• Preclinical metabolic-syndrome model research

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

AOD-9604 HGH fragment 176-191 — what is the research significance?

AOD-9604 is the C-terminal 16-residue fragment of human growth hormone (amino acids 176-191). It retains the lipolytic activity of intact hGH but does not activate the IGF-1 axis, isolating adipose-tissue research from broader growth-signal confounders.

Buy AOD-9604 peptide with certificate of analysis?

Advanced Peptide Science supplies AOD-9604 at 99%+ HPLC-verified purity with batch-specific Certificates of Analysis available at research@advancedpeptidescience.com.

Is AOD-9604 approved for human use?

Advanced Peptide Science supplies AOD-9604 exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.