TB-500

Overview

Researchers can buy TB-500 research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. TB-500 is a synthetic analogue of the actin-binding fragment of Thymosin Beta-4 (sequence LKKTETQ, residues 17-23 of the parent 43-amino-acid protein), with a molecular weight of 899.0 Da.

Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.

Research Background

Thymosin Beta-4 is a naturally occurring G-actin-sequestering protein involved in cytoskeletal dynamics, cellular migration, and tissue repair. TB-500 represents the bioactive actin-binding domain in synthetic form for research economy. The compound is widely paired with BPC-157 in dual regenerative protocols investigating complementary mechanisms.

Mechanism of Action (Research Context)

Mechanism research focuses on TB-500’s sequestration of monomeric G-actin via the actin-binding LKKTETQ motif, which influences cytoskeletal polymerisation dynamics and cellular migration capacity. Downstream pathways under investigation include angiogenic signalling, inflammatory pathway modulation, and extracellular matrix remodelling in tissue-repair models.

Research Applications

• G-actin sequestration and cytoskeletal dynamics research
• Cellular migration and wound-repair model investigation
• Angiogenesis and extracellular matrix remodelling studies
• Combined investigation with BPC-157 for dual regenerative mechanism research
• Multi-compound research via Glow Blend and KLOW Blend

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

Buy TB-500 Thymosin Beta-4 research peptide USA COA?

Advanced Peptide Science supplies TB-500 at 99%+ HPLC-verified purity with batch-specific COA available on request.

TB-500 BPC-157 research stack — what is the rationale?

BPC-157 acts via EGR-1/VEGFR2 cytoprotection pathways while TB-500 acts via G-actin sequestration and cellular migration. Researchers investigate the two compounds together to study complementary regenerative mechanisms — available as the pre-formulated BPC-157 + TB-500 Blend.

Is TB-500 approved for human use?

Advanced Peptide Science supplies TB-500 exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.