Overview
Researchers in sleep neurobiology can buy DSIP research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. DSIP (Delta Sleep-Inducing Peptide) is a nonapeptide neuropeptide with sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu and a molecular weight of 848.9 Da, originally isolated from rabbit thalamic tissue.
Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.
Research Background
DSIP was discovered in the early 1970s through fractionation of rabbit thalamic tissue extracts that induced delta-wave sleep patterns. The molecular target of DSIP remains an active area of research investigation — making the compound a research tool for studying sleep-architecture regulation independent of GABAergic or melatonergic mechanisms.
Mechanism of Action (Research Context)
Mechanism research investigates DSIP effects on sleep architecture (notably delta-wave activity), inhibition of ACTH release from the pituitary, modulation of antioxidant enzyme expression in stress models, and stress response pathway studies. Electroencephalographic pattern research is a major application area.
Research Applications
- Sleep architecture pathway modulation research
- ACTH release inhibition mechanism studies
- Antioxidant enzyme expression and oxidative-stress pathway research
- Stress response neuropeptide investigation
- Electroencephalographic pattern research in preclinical models
Compound Specifications
| Molecular Weight | 848.9 Da |
| Sequence / Composition | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE) — nonapeptide |
| Appearance | White lyophilized powder |
| Purity | ≥ 99% (HPLC verified) |
| Storage | -20 °C, protect from light |
| Format | Lyophilized powder in sterile vial |
Quality Assurance
Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.
Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.
Frequently Asked Questions
Buy DSIP delta sleep inducing peptide research USA COA?
Advanced Peptide Science supplies DSIP at 99%+ HPLC-verified purity with batch-specific COA available on request.
DSIP sleep cycle research peptide — mechanism?
DSIP was identified as a thalamic-tissue-derived factor inducing delta-wave sleep patterns. Its specific molecular target remains under investigation, making DSIP a research tool for sleep-architecture pathway studies distinct from GABAergic or melatonergic mechanisms.
Is DSIP approved for human use?
Advanced Peptide Science supplies DSIP exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.


