Overview
Immunology researchers can buy Thymosin Alpha-1 research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. Thymosin Alpha-1 (thymalfasin) is a 28-amino-acid N-terminally acetylated peptide naturally produced by the thymus gland, with a molecular weight of 3108.4 Da.
Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.
Research Background
Thymosin Alpha-1 was first isolated from the thymic fraction 5 extract in the 1970s. The N-terminal acetylation is essential for biological activity. The compound has been extensively researched in immune modulation studies and serves as a foundational immune-peptide research tool for investigations into thymic-derived immune signalling.
Mechanism of Action (Research Context)
Mechanism research investigates Thymosin Alpha-1 activation of Toll-like receptors (notably TLR9 and TLR2) on dendritic cells, leading to enhanced dendritic cell maturation, IL-12 production, and Th1-skewed T-cell response polarisation. Additional research examines T-cell proliferation enhancement and antiviral immune response pathway studies.
Research Applications
- Toll-like receptor (TLR9/TLR2) pathway activation research
- Dendritic cell maturation and antigen presentation studies
- T-cell proliferation and Th1-response polarisation research
- Antiviral immune response preclinical model investigation
- Comparative immune modulation research vs Vilon bioregulator
Compound Specifications
| Molecular Weight | 3108.4 Da |
| Sequence / Composition | 28-amino-acid N-terminally acetylated thymic peptide (thymalfasin) |
| Appearance | White lyophilized powder |
| Purity | ≥ 99% (HPLC verified) |
| Storage | -20 °C, protect from light |
| Format | Lyophilized powder in sterile vial |
Quality Assurance
Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.
Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.
Frequently Asked Questions
Buy Thymosin Alpha-1 immune-modulating peptide USA COA?
Advanced Peptide Science supplies Thymosin Alpha-1 at 99%+ HPLC-verified purity with batch-specific COA available on request.
Thymosin Alpha-1 antiviral research peptide — mechanism?
Thymosin Alpha-1 activates Toll-like receptors on dendritic cells, enhancing antigen presentation and skewing T-cell responses toward Th1 (cellular immunity). This makes it a research tool for antiviral immune signalling investigation.
Is Thymosin Alpha-1 approved for human use?
Advanced Peptide Science supplies Thymosin Alpha-1 exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.


