Semax

Overview

Cognitive and neuroprotection researchers can buy Semax research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. Semax is a synthetic heptapeptide ACTH 4-7 analogue (sequence Met-Glu-His-Phe-Pro-Gly-Pro, MW 813.9 Da) supplied as lyophilized powder for nasal solution reconstitution.

Research Background

Semax was developed by the Institute of Molecular Genetics at the Russian Academy of Sciences in parallel with Selank, as part of a programme designing synthetic neuropeptides with extended bioavailability via the nasal/intranasal delivery route. Its ACTH 4-7 backbone with C-terminal Pro-Gly-Pro extension confers protease resistance and intranasal absorption.

Mechanism of Action (Research Context)

Mechanism research investigates Semax-induced upregulation of BDNF expression in hippocampal and cortical neurons, modulation of serotonergic, dopaminergic, and cholinergic neurotransmitter systems, and neuroprotective signalling in ischaemia preclinical models. ACTH receptor pharmacology and downstream MC-receptor signalling are areas of active comparative investigation.

Research Applications

• BDNF upregulation and synaptic plasticity research
• Serotonin, dopamine, and acetylcholine system modulation studies
• Neuroprotective mechanism investigation in ischaemia models
• Intranasal delivery pharmacokinetics research
• Combined investigation with Selank for Russian neuropeptide stack research

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

Semax ACTH analogue BDNF neuropeptide research USA COA?

Advanced Peptide Science supplies Semax at 99%+ HPLC-verified purity with batch-specific COA available on request.

Buy Semax nasal research peptide — what format?

Semax is supplied as lyophilized powder for nasal solution reconstitution. Storage -20 °C lyophilized; 2-8 °C after reconstitution.

Is Semax approved for human use?

Advanced Peptide Science supplies Semax exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.