Tesamorelin

Overview

Researchers in GHRH-analogue pharmacology and visceral adipose biology can buy Tesamorelin research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. Tesamorelin is a 44-amino-acid GHRH analogue with a trans-3-hexenoic acid modification at the N-terminus, with a molecular weight of 5135.0 Da. It is the longest-chain GHRH analogue in standard research supply.

Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.

Research Background

Tesamorelin retains the full-length GHRH (44 amino acids) backbone — distinct from the truncated Sermorelin (29 residues) — while incorporating an N-terminal trans-3-hexenoic acid modification that stabilises the peptide against DPP-4 degradation and extends its preclinical half-life. The compound has been investigated specifically for effects on visceral adipose tissue beyond the general GH-axis stimulation profile of other GHRH analogues.

Mechanism of Action (Research Context)

Mechanism research investigates Tesamorelin binding at GHRHR (class B GPCR) on pituitary somatotrophs with downstream Gs/cAMP signalling driving GH secretion. Downstream lipid-metabolism research focuses on the effect of pulsatile GH-axis stimulation on visceral adipose tissue and hepatic lipogenesis pathways — endpoints distinct from purely linear height/IGF-1 research.

Research Applications

• Full-length (44-residue) GHRH analogue receptor research
• Visceral adipose tissue mechanism investigation
• GH-axis activation with lipid-metabolism research endpoints
• Comparative research vs Sermorelin (29-residue GHRH 1-29)
• DPP-4 stability research with N-terminal modification

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

Buy Tesamorelin GHRH analogue visceral fat research USA?

Advanced Peptide Science supplies Tesamorelin at 99%+ HPLC-verified purity with batch-specific COA available on request.

Tesamorelin 2mg research peptide COA verified — what is the modification?

Tesamorelin is a 44-residue GHRH analogue with a trans-3-hexenoic acid modification at the N-terminus, conferring DPP-4 protease resistance and extending preclinical half-life vs unmodified GHRH (1-44).

Is Tesamorelin approved for human use?

Advanced Peptide Science supplies Tesamorelin exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.