Hexarelin

Overview

Researchers in growth hormone axis and cardiac peptide research can buy Hexarelin research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. Hexarelin (also called Examorelin) is a synthetic hexapeptide GHRP with sequence His-D-2-MeTrp-Ala-Trp-D-Phe-Lys-NH2 and a molecular weight of 887.1 Da.

Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.

Research Background

Hexarelin is one of the most potent GH-releasing GHRPs in the class. Beyond its GHS-R1a agonism, research identified Hexarelin binding at the scavenger receptor CD36 in cardiac tissue, opening a research line investigating direct cardioprotective signalling independent of GH-pathway effects. Compare against GHRP-6 and GHRP-2 for relative potency and receptor profile research.

Mechanism of Action (Research Context)

Mechanism research investigates two parallel pathways: GHS-R1a-mediated Gq/PLC signalling at pituitary somatotrophs driving GH pulse amplification, plus CD36 binding in cardiac tissue driving downstream cardioprotective signalling cascades. The dual-receptor profile distinguishes Hexarelin from other GHRPs and is the focus of significant comparative pharmacology research.

Research Applications

• GHS-R1a agonism and high-potency GH-release research
• CD36 binding and cardioprotective signalling pathway investigation
• Cardiac tissue receptor pharmacology independent of GH axis
• GH pulse magnitude comparison research vs GHRP-6 and GHRP-2
• Multi-receptor GHRP pharmacology comparative studies

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

Buy Hexarelin Examorelin research peptide USA COA?

Advanced Peptide Science supplies Hexarelin at 99%+ HPLC-verified purity with batch-specific COA available on request.

Hexarelin cardioprotective research peptide — what receptors?

Hexarelin binds both GHS-R1a (driving GH pulse amplification) and CD36 in cardiac tissue (driving cardioprotective signalling independent of GH). The CD36 binding distinguishes Hexarelin from other GHRPs.

Is Hexarelin approved for human use?

Advanced Peptide Science supplies Hexarelin exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.