GHRP-2

Overview

Researchers can buy GHRP-2 research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity. GHRP-2 (also known as Pralmorelin) is a synthetic hexapeptide ghrelin receptor (GHS-R1a) agonist with sequence H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 and a molecular weight of 817.9 Da.

Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.

Research Background

GHRP-2 was developed as a refinement of the original GHRP-class compounds, including GHRP-6 and Hexarelin. It maintains the GHS-R1a agonism core mechanism but with structural changes that shift the receptor binding profile and reduce appetite-stimulation side effects relative to GHRP-6.

Mechanism of Action (Research Context)

Mechanism research investigates GHRP-2 binding at GHS-R1a with downstream Gq/PLC signalling driving GH-pulse-magnitude amplification at the pituitary somatotrophs. Comparative research against GHRP-6 examines receptor binding affinity, downstream pathway activation differences, and the relative magnitude of secondary effects (cortisol, prolactin, appetite-pathway engagement).

Research Applications

• GHS-R1a binding affinity comparison research vs other GHRPs
• GH-pulse-magnitude pharmacology studies
• Pituitary somatotroph response model research
• Selective vs non-selective GHRP comparison studies
• Comparative research with GHRP-6 and Hexarelin

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

Buy GHRP-2 Pralmorelin research peptide USA?

Advanced Peptide Science supplies GHRP-2 (Pralmorelin) at 99%+ HPLC-verified purity with batch-specific COA available on request.

GHRP-2 GHRP-6 comparison research?

Both are hexapeptide GHS-R1a agonists. GHRP-2 (817.9 Da) is reported to have reduced appetite-stimulation relative to GHRP-6 (873.0 Da) in preclinical models, useful for isolating GH-axis effects from appetite-pathway effects.

Is GHRP-2 approved for human use?

Advanced Peptide Science supplies GHRP-2 exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.