CJC-1295 + Ipamorelin Blend

Overview

Researchers in growth hormone axis investigation can buy CJC-1295 Ipamorelin blend research peptide from Advanced Peptide Science at 99%+ HPLC-verified purity per compound. The blend co-formulates CJC-1295 (MOD-GRF 1-29, a 29-residue GHRH analogue with DAC modification for extended half-life, 3367.9 Da) with Ipamorelin (a selective pentapeptide GHRP with a low side-effect profile, 711.9 Da).

Bacteriostatic Water (BAC Water) 30ml is required for reconstitution of this lyophilized compound. Available separately: Bacteriostatic Water 30ml.

Research Background

The CJC-1295 + Ipamorelin pairing is a foundational GHRH/GHRP research stack — combining a GHRH receptor agonist that drives baseline GH-axis stimulation with a selective ghrelin-mimetic GHRP that amplifies the pulse magnitude. The blend format simplifies co-administration in preclinical pulsatility studies and serves as a comparator for alternative GHRH (Sermorelin, Tesamorelin) and GHRP (GHRP-6, GHRP-2, Hexarelin) combinations.

Mechanism of Action (Research Context)

Mechanism research investigates simultaneous activation of two pituitary somatotroph receptor systems: GHRH-receptor-mediated Gs/cAMP signalling driving GH gene transcription and baseline secretion, plus GHS-R1a-mediated Gq/PLC signalling driving GH-pulse-magnitude amplification. The Ipamorelin component is selected for its receptor selectivity — it does not significantly stimulate cortisol or prolactin release in preclinical models, unlike earlier GHRPs.

Research Applications

• GHRH-receptor + GHS-R1a co-activation pharmacology research
• Pulsatile GH secretion magnitude and frequency studies
• Selective GHRP (Ipamorelin) vs non-selective GHRP receptor research
• Comparative GHRH-analogue research vs Sermorelin and Tesamorelin
• Multi-compound research via GH Blend (CJC-1295 + Ipamorelin + GHRP-6)

Compound Specifications

Quality Assurance

Each batch is independently verified by third-party analytical laboratories. Certificates of Analysis confirming ≥99% purity via HPLC are available on request at research@advancedpeptidescience.com.

Research Use Only. For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing you confirm research-only intent. These products have not been evaluated by the FDA.

Frequently Asked Questions

CJC-1295 Ipamorelin blend 10mg research vial USA COA?

Advanced Peptide Science supplies the CJC-1295 + Ipamorelin Blend at 99%+ HPLC-verified purity per compound, with batch-specific Certificates of Analysis available on request.

Why combine GHRH and GHRP in research?

GHRH analogues drive baseline GH-axis stimulation via Gs/cAMP at pituitary somatotrophs; GHRPs amplify pulse magnitude via Gq/PLC at GHS-R1a. Co-administration is investigated for synergistic GH-axis research vs either compound alone.

Is this blend approved for human use?

Advanced Peptide Science supplies this blend exclusively for in vitro and in vivo scientific research. Not for human consumption. Research use only.